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Kashmiri scientist in Harvard links cancer treatment strategy to fix Alzheimer’s

Most Alzheimer’s cases are late-onset. Vijay Kuchroo’s study found TIM-3, an immune checkpoint molecule, stops brain cells from clearing harmful plaques linked to the disease.

Vijay Kuchroo. / Harvard Gazette

Vijay Kuchroo, an Indian-American immunologist and senior author of a groundbreaking new study, believes an immune system strategy already used to treat cancer could one day help patients battling Alzheimer’s disease.

Born in Baramulla, Jammu & Kashmir, India, Kuchroo is now the Samuel L. Wasserstrom professor of Neurology at Harvard Medical School and Brigham and Women’s Hospital, and directs the Evergrande Center for Immunologic Diseases in Boston. Speaking to the Harvard Gazette, he discussed his team’s research, published this month in Nature, which explores the role of a molecule called TIM-3 in late-onset Alzheimer’s.

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