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Gender-specific symptoms experienced before impending cardiac arrest

The study revealed that symptoms vary depending on the individual’s gender

A study conducted by the Smidt Heart Institute at Cedars-Sinai Medical Center in Los Angeles, spearheaded by Sumeet Chugh, a specialist in sudden cardiac arrest, discovered that 50 per cent of individuals encountered warning signals before experiencing cardiac arrest.

Under the leadership of Chugh, the team observed a divergence in the warning symptoms between women and men. The findings detailed in the peer-reviewed journal Lancet Digital Health, revealed that women commonly faced shortness of breath as the predominant precursor to sudden cardiac arrest, while men were more likely to undergo chest pain.

In addition, smaller subgroups within both genders reported experiencing palpitations, seizure-like episodes, and symptoms reminiscent of flu, the findings showed.

“Harnessing warning symptoms to perform effective triage for those who need to make a 911 call could lead to early intervention and prevention of imminent death,” said Chugh, director of the Center for Cardiac Arrest Prevention in the Smidt Heart Institute and senior author of the study. “Our findings could lead to a new paradigm for prevention of sudden cardiac death.”

Chugh holds the distinguished title of the Pauline and Harold Price Professor of Cardiac Electrophysiology. He also serves as the associate director of the Heart Institute, the medical director of the Heart Rhythm Center, and the director of the Division of Artificial Intelligence in Medicine at Cedars-Sinai.

Additionally, Chugh is a professor of Medicine-in-Residence at the David Geffen School of Medicine at UCLA. Throughout his scientific journey, Chugh's focus has centred on discovering innovative methods for predicting and preventing sudden cardiac death. His contributions have earned him membership in esteemed organizations such as the American Society for Clinical Investigation and the Association of American Physicians.

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